Approximately 30% of
all patients with type 2 diabetes will
develop diabetic nephropathy (DN). Still
there are no effective methods to
determine the individual risk of developing DN. Duration
of diabetes as well as glycaemic and
blood pressure control do not
sufficiently explain the risk of
developing DN.
About 31 genes and many other factors have been suspected to
contribute to the development of DN. A
major gene has been
mapped to 18q and was identified to
cause a 3-fold elevated risk of DN.
The aim of this project is to
identify pathophysiologically relevant
genes and biomarkers correlated to the
development, progression and
therapy of DN.
Predictions is an EU-funded network (6th
Framework; funding period: 2005-2008)
PREDICTIONS is an EU-funded network
(6th Framework; funding period:
2005-2008). The project started
01.12.2005.
PREDICTIONS is an acronym for
PREvention of DIabetic
ComplicaTIONS.
The PREDICTIONS network unites
research groups from 7 different
European Universities and 2 SME's (see
'About Us')
The aim of the project is to
identify pathophysiologically
relevant genes and biomarkers
correlated to the development,
progression and therapy of DN.